Infectious Disease OutbreaksPathogen

Long COVID fluvoxamine evidence dispute

March 31, 2026Ian Weissman, DO, Todd Davenport

Ian Weissman claims a low cost antidepressant treats long COVID fatigue, while Todd Davenport pushes back that there is not convincing evidence it works, reflecting ongoing uncertainty about pharmacologic options.

A common and low-cost antidepressant can successfully treat fatigue associated with long COVID.
It is one of the first times a medication has been shown to effectively treat the condition.
Honestly it doesn't matter *how* fluvoxamine might work in Long Covid. We don't have convincing evidence *that* it worked.
Ian Weissman, DO
Todd Davenport
Long COVIDevidence quality

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