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Lenacapavir twice yearly HIV prevention and affordability debate

April 5, 2026r/medicine

In r/medicine, clinicians debate lenacapavir as near complete HIV prevention with twice yearly dosing, while criticizing pricing, access barriers, and perceived production limits that could blunt public health impact.

There’s a drug called lenacapavir that can prevent HIV infections almost completely.
You only need to take it twice a year instead of daily pills.
They are limiting production heavily to make shareholders happy.
Insurance was initially covering it, but they seem to be reneging on that, which isn’t great.
At my clinic, we spend a lot of time getting it covered and whatnot.
r/medicine
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