Clinical Research And EvidenceFinding

Inhaled sevoflurane sedation worse outcomes than propofol in ARDS

April 1, 2026JAMA

JAMA reports that in moderate to severe ARDS, inhaled sevoflurane sedation led to fewer ventilator-free days and lower 90-day survival than intravenous propofol, with safety concerns including acute kidney injury.

In adults with moderate to severe #ARDS, inhaled sevoflurane sedation produced fewer ventilator-free days and lower 90-day survival than intravenous propofol, raising safety concerns including acute kidney injury.
JAMA
ARDSICU sedation

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