Clinical Research And EvidenceFinding

Humans assisted by an LLM performed worse than the LLM alone in medical scenarios

April 2, 2026Nature Medicine

Nature Medicine reports a randomized study where human performance with LLM assistance was inferior to the LLM alone across 10 medical scenarios, raising concerns about how assistance is integrated into clinical reasoning.

In a randomized controlled study of 1,298 participants, performance of humans when assisted by an #LLM was inferior to the LLM alone when assessing 10 medical scenarios.
Nature Medicine
LLMclinical decision support

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