Chronic Disease And CancerCondition

GLP 1 medications and procedural sedation safety from delayed gastric emptying

April 6, 2026NEJM Clinician

NEJM Clinician notes concerns that GLP-1-based delayed gastric emptying could affect safety during sedation-required procedures, and points to a randomized trial evaluating the issue.

Concerns have been raised about whether the delayed gastric emptying caused by GLP-1–based medications might jeopardize patient safety during procedures that require sedation.
A randomized trial takes a closer look.
NEJM Clinician
GLP-1perioperative

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