Chronic Disease And CancerCondition

Evolocumab LDL lowering for primary prevention in diabetes

April 4, 2026JAMA Network

JAMA Network reports VESALIUS-CV results suggesting evolocumab plus statin reduced first major cardiovascular events in people with diabetes without known significant atherosclerosis, supporting more intensive LDL-C lowering in selected patients.

Evolocumab for Heart Protection in People With Diabetes
intensive LDL-C lowering with evolocumab plus statin reduced risk of first major cardiovascular event vs placebo
VESALIUS-CV trial
JAMA Network
cardiometaboliclipidsdiabetes

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