Infectious Disease OutbreaksPathogen

Empiric atypical coverage in non-severe community acquired pneumonia

April 4, 2026Antibiotic Steward Bassam Ghanem 🅱 C🆔🅿

Bassam Ghanem points to a large propensity-weighted target trial emulation suggesting no key outcome differences with empiric atypical coverage in non-severe community acquired pneumonia, challenging routine prescribing.

Time to revisit empiric atypical coverage in non-severe CAP?
Target trial emulation using a propensity-weighted cohort from 68 hospitals in Michigan >66,000 patients:
• No difference in time to clinical stability
Target trial emulation
from 68 hospitals in Michigan >66,000 patients:
No difference in time to clinical stability
Antibiotic Steward Bassam Ghanem 🅱 C🆔🅿
CAPantibiotic stewardship

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