Harriette Van Spall highlights an ACC26 randomized trial claiming digoxin is effective, cheap, and reduces a composite of all-cause death or worsening heart failure in rheumatic heart disease, calling the 18 percent risk reduction huge.
Digoxin is effective, cheap, & ⬇️ composite ACD or WHF in rheumatic heart disease, which affects 54.8 million ppl in world
An 18% risk reduction is HUGE for a pragmatic investigator initiated RCT
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