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GLP-1 receptor agonists clinical mainstreaming

April 1, 2026NEJM, Eric Topol, Keith Siau

NEJM highlights GLP-1 receptor agonists for diabetes and obesity with cardiovascular and kidney benefits, while Eric Topol and Keith Siau amplify the same NEJM review as a key reference point.

GLP-1 receptor agonists are increasingly used to treat type 2 diabetes and obesity
trials have shown reductions in cardiovascular risk and slowing of kidney failure.
Adverse events are mostly gastrointestinal.
A new review of the GLP-1 receptor drugs
GLP1 agonists - April 2026 NEJM review
NEJM
Eric Topol
Keith Siau
obesitydiabetescardiorenal

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