Clinical Research And EvidenceStudy Finding

CHIP-BCIS3 Impella left ventricular unloading in high risk PCI no benefit

March 29, 2026TCTMD, NEJM, Mamas A. Mamas

TCTMD and NEJM frame CHIP-BCIS3 as evidence that microaxial flow pump support in high-risk PCI did not improve outcomes and may cause harm.

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QUOTES

Impella Support in High-Risk PCI Doesn’t Help, Might Harm: CHIP-BCIS3

Original Article: Left Ventricular Unloading in High-Risk Percutaneous Coronary Intervention (CHIP-BCIS3 trial)

Editorial: Price of Protection — Microaxial Flow Pump in High-Risk PCI

VOICES

TCTMD

NEJM

Mamas A. Mamas

RELATED TERMS

trialPCIdevices

OTHER FINDINGS IN CLINICAL RESEARCH AND EVIDENCE

ORBITA-CTO sham-controlled trial showing angina improvement beyond placebo HPV vaccination linked to sharp decline in US cervical cancer among young women CHIP-BCIS3 trial finding no benefit from elective LV unloading with microaxial flow pump in complex PCI

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