Chronic Disease And CancerCondition

Atezolizumab added to mFOLFOX6 improving DFS in resected stage III dMMR colon cancer (ATOMIC)

March 30, 2026NEJM

NEJM reports ATOMIC: adding atezolizumab to modified FOLFOX6 improved 3-year disease-free survival in resected stage III mismatch repairdeficient colon cancer, with more grade 34 toxic effects mainly fatigue.

In the phase 3 ATOMIC trial in resected stage III mismatch repair–deficient colon cancer, adding atezolizumab to modified FOLFOX6 improved 3-year disease-free survival, with a higher incidence of grade 3 or 4 toxic effects, mainly fatigue.
NEJM
colon cancerimmunotherapy

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