Pulse/Artificial Intelligence
Local Ai Hardware And PerformanceHardware Setup

Multi-GPU local LLM rigs for running Qwen with vLLM

March 25, 2026r/LocalLLaMA

In r/LocalLLaMA, builders share cost-optimized home GPU setups to run larger models locally, emphasizing VRAM-per-dollar and creative PCIe expansion via NVMe adapters.

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QUOTES
Around the SAME time I also impulsed bought 128GB DDR5
Instead its now running Qwen3.5-27B with vllm on 4x RTX 5060 Ti which imho was the best value for money for a combined 64GB of VRAM.
The motherboard has 2x PCIe slots, but a bunch of NVMe slots, so I bought NVMe to PCIe adapters
VOICES
r/LocalLLaMA
RELATED TERMS
runs locallyhardwarevramruns locally
OTHER FINDINGS IN LOCAL AI HARDWARE AND PERFORMANCE
H100-driven repeated-layer experiments on Qwen3.5 27BFlashAttention-4 and vLLM inference speedups on B200Edge-board and Mac-focused local LLM/VLM inference performance comparisons
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